Funding transnational collaborative research through joint transnational calls is one of the major objectives of E-Rare. This is the most important and effective joint activity to enhance the cooperation between European scientists working on rare diseases and thus reducing the fragmentation of research in this field. E-Rare launches calls on a yearly basis. The topic and eligibility criteria are specified every year and therefore may vary from one call to the other.

FAQ

Questions

Proposal submission

Eligibility

Collaboration - research groups

Budget

Funding

Evaluation

Answers

Proposal submission

In order to submit your proposal you should register via the PT-outline system. The link to the registration and submission is given in the Open call General Information under the "Registration" paragraph.

Research consortia who intend to submit a transnational project proposal should register at the electronic proposal system as soon as possible via the link provided in the Open Call section.
The system will be opened in the second week of January latest. To register, please fill in the data sheet of the system. The same data sheet can later be used for the final electronic proposal submission. It is mandatory to use the electronic submission system and proposals, which have not been uploaded via the electronic submission system will be rejected.

In many cases it is helpful to contact the national contact point personally. They can provide specific information about national regulations, specific characteristics and national budget. The list of National contact points is accessible via Open Call - National contact points section.

A proposal template can be downloaded from Open Call - Download documents section. Using this template is mandatory. Proposals not meeting the formal criteria of the template will be rejected without further review.

The pre-proposal template requirements are the following:

  • Description of the project: max. 5 pages DIN-A4, Arial 11, single-spaced, margins of 1.27)
  • Diagrams of the work plan, timeline, work flow and interconnections of work packages (Gantt chart, Pert or similar, max. 1 page)
  • Additional two more pages containing: appendix with references (one page maximum) and diagrams, figures, etc. (one page maximum)
  • Academic CV (max. 1 page) with 5 most relevant publications for each participating principal investigator.

Yes, this is possible. However, it is not recommended to act as a coordinator in several proposals.

At least, the following documents are necessary:

  • Pre-proposal form
  • Pre-eligibility check form (only for Italian groups)
  • Call text
  • Guidelines for applicants
  • Full proposal form (only at the second stage)

All documents are available in the Open Call - Download documents section.

 

No, no exceptions are possible. The electronic submission system will be closed at 17:00 GMT on the day of the deadline. No proposal submission is possible thereafter. We recommend to finalising your proposal in advance.

Eligibility

No, the project is evaluated based on the scientific excellence and the country from which the coordinator is coming does not influence the evaluation note. However, the participation of parners from Eastern countries is considered as an added value for the project at the condition that the presence of such a group is justified by complementarity and scientific need for the project.

Yes. The coordinator of a running project previously funded by E-Rare may apply with a new project. What is important is the role of the coordinator in this new project. In case if the coordinator of currently running funded project wants to apply he/she needs to make sure that the workload claimed for the two project (running and new) does not exceed 100% and that he/she will be able to run both projects (in case if the new one is recommended for funding).

Yes. Amyotrphic Lateral Sclerosis (ALS) is consdered a rare disease. According to the Orphanet source (www.orpha.net) its prevalence is estimated to 1 - 9/100 000.

However for the E-Rare JTC 2015 ALS is excluded from the scope of the call since it falls under the Motor neuron diseases (MND) that are being financed under the Joint Programming Initiative on Neurodegenerative Disease Resarch (JPND).

The inclusion of a non-eligible partner in a proposal leads to the rejection of the entire proposal without further review. Whilst applications will be submitted jointly by partners from several countries, individual groups will be funded by the individual funding organisation of their country/region that is participating in the E-Rare Joint Transnational Call. The applications are therefore subjected to eligibility criteria of individual funding organisations. Applicants are strongly advised to contact their corresponding national/regional representative and confirm eligibility with their respective funding organisations in advance of submitting an application (see Call text document and national/regional contact details in Open Call section).

The eligibility criteria are specific to each country participating in the call. Please refer to the relevant Call text and country specific information specified in the Guidelines for Applicants. All necessary documents are available in Open Call - Download documents section.

Collaboration - research groups

Yes, a partner from any country participating in the Joint Call can be a coordinator of a project. However, as a coordinator or a partner, the applicant should make sure that he/she fulfills the eligibility criteria of its national funding agency.

The partners from countries non-participating in the call may be a part of the project as a full partner as long as they assure their own funding. This means that their contribution to the project will be covered from for ex. national grant. Such a partner should not be funded by other partners of the consortium since this would be considered as subcontracting. If a consortium decides to include a non-eligible partner as subcontractor this partner does not have a status of full partner in the project but only of a subcontractor. The subcontracting rules must comply with national funding rules of the partner that decides to cover the cost of the subcontractor.

The size of the consortium is not a review criteria, as long as the formal criteria will be considered (see Call text). However the number of groups in a consortium should not exceed six (if no partners from Eastern European countries participate in the project) or eight (in case if partners from Eastern European countries participate in the project) and participation of each group should be well justified.

Yes, in principle this is possible. However the maximum number of eligible for funding partners from the same country is limited to two per project.

Each consortium submitting a proposal must involve a minimum of three partners from three different countries participating to the call. All three partners must be eligible for funding (see National/regional regulations in the Guidelines for applicants).

In case if no partners from Eastern European countries are included a maximum of six partners can participate in the project. If partners from Eastern European countries are a part of the consortium (see Call texta nd Guidelines) a maximum of eight partners can participate in the project.

There must be no more than two eligible partners from the same country per project.

Partners from countries that are not participating in Joint Transnational Call (for example: USA, China etc) may participate in the projects if they are able to secure their own funding. It must be stated clearly in the proposal if these funds are already secured or, if not, how they plan to obtain funding in advance of the project start. It will be required to document the availability of their funds before October 1st (of the year when the funding decision is communicated). Nevertheless the overall maximum number of eligible partners in a given consortium should be maintained at six (if no partners from Eastern Euroepan countries are included) or at eight (if partners from Eastern European countries are included).

Budget

No. No changes in the budget are acceptable. The budget indicated in the pre-proposal should remain the same in the full proposal.

The eligibility of overheads depends on the national regulations. Please refer to the Call text and Guidelines for applicants documents that are available on Open Call - Download documents section. In case of question contact your National contact point.

The budget of the proposal should depend on the work plan, effort, duration, and on specific national regulations. Please see country specific information table (included in the call text) or ask your national contact point in case of questions.

Yes, the average funding amount, the avilability of budget and the funding amount is decided by the national funding organizations each year. For more details please refer to the documents of the on-going call and country specific information in the call text.

The eligibility of costs, types and their caps is dependent on national regulations of individual funding agencies. Please refer to country specific information in the call text or ask your national contact point in case of questions.

Funding

The CSC (Call Steering Committee) will decide on the funding of proposals that are recommended for funding and try to solve all upcoming funding problems as far as possible. Nevertheless, it is possible that the whole consortium will not be funded if only one country cannot fund its research group.

The separate Scientific Evaluation Committee (SEC), which will be composed of internationally renowed scientists from the field of rare diseases, will establish a ranking list for the proposals, based on the scientific assessment and a treshold above which projects will be fundable.

Based on this ranking list the Call Steering Committee (CSC)* will make the final funding recommendation to the national/regional funding organisations on the proposals to be funded and taking into account the national budgets available.

Final decisions are made by the national funding agencies and are subject to budgetary considerations.

* The CSC is composed of a single representative from each country/region funding organisation. The CSC will supervise the progress of the call and the evaluation of proposals.

Evaluation

Pre-proposals and full proposals will be assessed according to specific evaluation criteria (see below), using a common evaluation form. A scoring system from 0 to 5 will be used to evaluate the proposal’s performance with respect to the different evaluation criteria.

Scoring system:
0: fails or missing/incomplete information
1: poor
2: fair
3: good
4: very good
5: excellent

Evaluation criteria:

1. Excellence

  • Clarity and pertinence of the objectives
  • Credibility of the proposed approach and methodology
  • Soundness of the concept
  • Innovative potential
  • Competence and experience of participating research partners in the field(s) of the proposal (previous work in the field, specific technical expertise)

 2. Impact

  • Potential of the expected results for future clinical, public health and/or other socio-economic health relevant applications including  patients’ needs
  • Added-value of transnational collaboration: gathering a critical mass of patients/biological material, sharing of resources (models, databases, diagnosis etc.), harmonization of data, sharing of specific know-how and/or innovative technologies, etc.
  • Meaningful collaboration with Eastern European countries
  • Effectiveness of the proposed measures to exploit and disseminate the project results (including management of IPR), to communicate the project, and to manage research data where relevant
  • Industry and Patient Organization participation/engagement (when appropriate/applicable)

 3. Quality and efficiency of the implementation

  • Coherence and effectiveness of the work plan, including appropriateness of the allocation of tasks, resources and time-frame
  • Complementarity of the participants within the consortium
  • Appropriateness of the management structures and procedures, including risk and innovation management
  • Concept for sustainability of infrastructures initiated by the project
  • Budget and cost-effectiveness of the project (rational distribution of resources in relation to project’s activities, partners responsibilities and time frame)

Sub-criteria 2a and 2b will be prioritized for assessing the impact of proposals (pre- and full proposal stage).

Sub-criteria 2d, 2e, 3c, 3d and 3e will be taken into account only for the full proposal evaluation step.

Evaluation scores will be awarded for the 3 main criteria, and not singularly for the different aspects listed below the criteria. Each criterion will be scored out of 5. The threshold for individual criteria will be 3. The overall threshold, applying to the sum of the three individual scores, will be 12. The maximum score that can be reached from all three criteria together is 15 points.

If two proposals of similar focus are submitted, funding may be restricted to only the best of these two proposals. This does not mean that, as an example, only one proposal on Fanconi anemia can be funded. If the approach is different in may be possible to fund both proposals.

The reviewers are being selected for each Call by the Joint Call Steering Committee (CSC). The CSC consists of representatives of the call partner organizations. Please refer to the relevant Call text for more details of the review procedure.

E-Rare 2012 - Created by Toussaint Biger